mononuclear - Scrabble Dictionary

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Yes, "mononuclear" is a valid Scrabble word.

Valid in the following dictionaries

ENABLE (Words with Friends)

CSW (Scrabble UK/International)

having only one nucleus [adj] / a mononuclear cell [n -S]

NWL2020 (Scrabble US/Canada)

[n MONONUCLEARS]

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